Open AccessMicrobial Shifts and Shorter Time to Bowel Resection Surgery Associated with C. difficile in Pediatric Crohn’s Disease
Author(s) -
Jennifer Hellmann,
Heidi Andersen,
Fang Lin,
Aaron Linn,
Ramona Bezold,
Kathleen D. Lake,
Kimberly Jackson,
D. van Nuenen Meyer,
Kelsie Dirksing,
Erin Bonkowski,
Nicholas J. Ollberding,
David B. Haslam,
Lee A. Denson
Publication year - 2019
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1093/ibd/izz263
Subject(s) - clostridium difficile , medicine , carriage , odds ratio , hazard ratio , gastroenterology , crohn's disease , inflammatory bowel disease , retrospective cohort study , surgery , disease , confidence interval , microbiology and biotechnology , biology , pathology , antibiotics
Clostridioides difficile infection and colonization are common in pediatric Crohn's disease (CD). Our aims were to test the relationship between C. difficile positivity and bowel resection surgery and to characterize microbial shifts associated with C. difficile carriage and surgery.