Open AccessThe Treatment of Inflammatory Bowel Disease in Patients With a History of Malignancy
Author(s) -
Steve Lin,
Alex Goldowsky,
Konstantinos Papamichael,
Adam S. Cheifetz
Publication year - 2018
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1093/ibd/izy376
Subject(s) - malignancy , medicine , inflammatory bowel disease , disease , medical history , crohn's disease , inflammatory bowel diseases , intensive care medicine
As patients with inflammatory bowel disease (IBD) are living longer and our medical armamentarium expands, gastroenterologists are more frequently faced with treatment decisions about patients with IBD who also have a history of malignancy. This review aims to summarize the current literature on IBD, the inherent risk of developing gastrointestinal and extra-intestinal malignancies, and the risk of malignancies associated with available biologic and immunomodulatory therapies and to discuss the overall treatment strategy for a patient with a history of malignancy.