Open AccessCan Immune Checkpoint Inhibitors Induce Microscopic Colitis or a Brand New Entity?
Author(s) -
Kati Choi,
Hamzah Abu-Sbeih,
Rashmi Samdani,
Graciela Nogueras González,
Gottumukkala S. Raju,
David M. Richards,
Jianjun Gao,
Sumit K. Subudhi,
John R. Stroehlein,
Yinghong Wang
Publication year - 2018
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1093/ibd/izy240
Subject(s) - medicine , colitis , cancer , gastroenterology , diarrhea , colorectal cancer , population , cohort , retrospective cohort study , environmental health
Microscopic colitis (MC) has been described as 1 pattern of injury in immune checkpoint inhibitor (ICPI)-induced colitis. The main objective of this study was to characterize ICPI-induced MC by exploring the differences in risk factors, colitis treatments, endoscopic features, and clinical outcomes between cancer and noncancer patients with MC with and without exposure to ICPIs.