Open AccessMonocytosis Is a Biomarker of Severity in Inflammatory Bowel Disease: Analysis of a 6-Year Prospective Natural History Registry
Author(s) -
Alyce Anderson,
Cynthia Cherfane,
Benjamin Click,
Claudia Ramos-Rivers,
Ioannis Ε. Koutroubakis,
Jana G. Hashash,
Dmitriy Babichenko,
Gong Tang,
Michael A. Dunn,
Arthur Barrie,
Siobhan Proksell,
Jeffrey Dueker,
Elyse Johnston,
Marc Schwartz,
David G. Binion
Publication year - 2021
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1093/ibd/izab031
Subject(s) - monocytosis , medicine , inflammatory bowel disease , crohn's disease , disease , ulcerative colitis , immunology , gastroenterology , bone marrow
Inflammatory bowel disease (IBD) is associated with alterations of the innate and adaptive immune systems. Monocytes respond to inflammation and infection, yet the relationship between monocytosis and IBD severity is not fully understood. We aimed to characterize the prevalence of monocytosis in IBD and the association between monocytosis and disease severity and IBD-related health care utilization.