
Histologic Remission Is Associated With Lower Risk of Treatment Failure in Patients With Crohn Disease in Endoscopic Remission
Author(s) -
Hyuk Yoon,
Sushrut Jangi,
Parambir S. Dulai,
Brigid S. Boland,
Vipul Jairath,
Brian G. Feagan,
William J. Sandborn,
Siddharth Singh
Publication year - 2020
Publication title -
inflammatory bowel diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.932
H-Index - 146
eISSN - 1536-4844
pISSN - 1078-0998
DOI - 10.1093/ibd/izaa301
Subject(s) - medicine , hazard ratio , crohn's disease , gastroenterology , confidence interval , complete remission , surgery , retrospective cohort study , disease , chemotherapy
Although achieving histologic remission in ulcerative colitis is established, the incremental benefit of achieving histologic remission in patients with Crohn disease (CD) treated to a target of endoscopic remission is unclear. We evaluated the risk of treatment failure in patients with CD in clinical and endoscopic remission by histologic activity status.