Cumulative Histologic Inflammation Predicts Colorectal Neoplasia in Ulcerative Colitis: A Validation Study | Zendy

Olivia Yvellez | Zendy; Victoria Rai | Zendy; Philip H. Sossenheimer | Zendy; John Hart | Zendy; Jerrold R. Turner | Zendy; Christopher R. Weber | Zendy; Katia El Jurdi | Zendy; David T. Rubin | Zendy

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Cumulative Histologic Inflammation Predicts Colorectal Neoplasia in Ulcerative Colitis: A Validation Study

Author(s) -

Olivia Yvellez,

Victoria Rai,

Philip H. Sossenheimer,

John Hart,

Jerrold R. Turner,

Christopher R. Weber,

Katia El Jurdi,

David T. Rubin

Publication year - 2020

Publication title -

inflammatory bowel diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.932

H-Index - 146

eISSN - 1536-4844

pISSN - 1078-0998

DOI - 10.1093/ibd/izaa047

Subject(s) - ulcerative colitis , medicine , dysplasia , gastroenterology , cohort , colorectal cancer , inflammation , inflammatory bowel disease , confidence interval , colitis , cancer , disease

Chronic inflammation in ulcerative colitis (UC) is associated with the development of colorectal neoplasia (CRN). A group at St. Mark's Hospital reported a novel cumulative inflammatory index that predicted the development of CRN in UC patients that we validated with an independent, well-described, matched, case-controlled cohort from the University of Chicago.

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