Nanoparticles in pregnancy: the next frontier in reproductive therapeutics | Zendy

Natasha Pritchard | Zendy; Tu’uhevaha J. Kaitu’uLino | Zendy; Lynda K. Harris | Zendy; Stephen Tong | Zendy; Natalie J. Hannan | Zendy

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Nanoparticles in pregnancy: the next frontier in reproductive therapeutics

Author(s) -

Natasha Pritchard,

Tu’uhevaha J. Kaitu’uLino,

Lynda K. Harris,

Stephen Tong,

Natalie J. Hannan

Publication year - 2020

Publication title -

human reproduction update

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.977

H-Index - 180

eISSN - 1362-4946

pISSN - 1355-4786

DOI - 10.1093/humupd/dmaa049

Subject(s) - nanomedicine , medicine , pregnancy , intervention (counseling) , reproductive medicine , bioinformatics , nanotechnology , biology , nanoparticle , materials science , genetics , psychiatry

Nanotechnology involves the engineering of structures on a molecular level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic agents to a target site or organ in a controlled manner, maximizing efficacy while minimizing off-target effects of the therapeutic agent administered. In both reproductive medicine and obstetrics, developing innovative therapeutics is often tempered by fears of damage to the gamete, embryo or developing foetus or of negatively impacting a woman's reproductive potential. Thus, nanomedicine delivery systems may provide alternative targeted intervention strategies, treating the source of the disease and minimizing long-term consequences for the mother and/or her foetus.

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