Open AccessNewly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts
Author(s) -
Xiaohui Hu,
Qian Zhu,
Yan Wang,
Liling Wang,
Zhihui Li,
Gil Mor,
Aihua Liao
Publication year - 2020
Publication title -
human reproduction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.446
H-Index - 226
eISSN - 1460-2350
pISSN - 0268-1161
DOI - 10.1093/humrep/deaa223
Subject(s) - decidua , pregnancy , microbiology and biotechnology , treg cell , immunology , trophoblast , biology , andrology , medicine , placenta , t cell , immune system , fetus , il 2 receptor , genetics
What is the mechanism of Tim-3+ regulatory T (Treg)-cell accumulation in the decidua during early pregnancy and is its disruption associated with recurrent pregnancy loss (RPL)?
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