Open AccessLinks Between Inflammation, Mood, and Physical Function Among Older Adults With HIV
Author(s) -
Heather M. Derry,
Carrie Johnston,
Chelsie O Burchett,
Mark Brennan-Ing,
Stephen E. Karpiak,
YuanShan Zhu,
Eugenia L. Siegler,
Marshall J. Glesby
Publication year - 2021
Publication title -
the journals of gerontology. series b, psychological sciences and social sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.578
H-Index - 150
eISSN - 1758-5368
pISSN - 1079-5014
DOI - 10.1093/geronb/gbab027
Subject(s) - biopsychosocial model , medicine , psychosocial , loneliness , mood , psychological intervention , odds ratio , gerontology , depression (economics) , quality of life (healthcare) , clinical psychology , psychiatry , nursing , economics , macroeconomics
People living with human immunodeficiency virus (PLWH) treated with antiretrovirals have life spans similar to their HIV-negative peers. Yet, they experience elevated inflammation-related multimorbidity. Drawing on biopsychosocial determinants of health may inform interventions, but these links are understudied in older PLWH. We investigated cross-sectional relationships between psychosocial factors (mood, loneliness, and stigma), inflammatory markers, and age-related health outcomes among 143 PLWH aged 54-78 years.