Energetic Cost of Walking and Brain Atrophy in Mid-to-Late Life
Author(s) -
Ryan J. Dougherty,
Fangyu Liu,
Yang An,
Amal A. Wanigatunga,
Qu Tian,
Christos Davatzikos,
Eleanor M. Simonsick,
Luigi Ferrucci,
Susan M. Resnick,
Jennifer A. Schrack
Publication year - 2021
Publication title -
the journals of gerontology series a
Language(s) - English
Resource type - Journals
eISSN - 1758-535X
pISSN - 1079-5006
DOI - 10.1093/gerona/glab309
Subject(s) - brain size , gait , magnetic resonance imaging , physical medicine and rehabilitation , atrophy , white matter , preferred walking speed , neuroimaging , medicine , cardiology , psychology , neuroscience , radiology
Higher energetic costs for mobility are associated with declining gait speed, and slow gait is linked to cognitive decline and Alzheimer's disease. However, the physiological underpinnings of gait and brain health have not been well explored. We examined the associations of the energetic cost of walking with brain volume in cognitively unimpaired adults from the Baltimore Longitudinal Study of Aging.
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