Open AccessThe Importance of Muscle Versus Fat Mass in Sarcopenic Obesity: A Re-evaluation Using D3-Creatine Muscle Mass Versus DXA Lean Mass Measurements
Author(s) -
Eric S. Orwoll,
Katherine W. Peters,
Marc K. Hellerstein,
Steven R. Cummings,
William J. Evans,
Peggy M. Cawthon
Publication year - 2020
Publication title -
the journals of gerontology. series a, biological sciences and medical sciences
Language(s) - English
Resource type - Journals
eISSN - 1758-535X
pISSN - 1079-5006
DOI - 10.1093/gerona/glaa064
Subject(s) - sarcopenic obesity , sarcopenia , lean body mass , medicine , muscle mass , obesity , fat mass , adverse effect , physical therapy , body weight
The combination of sarcopenia and obesity has been associated with physical impairment in older people. However, previous research has relied on assessments of lean mass as a surrogate for muscle mass. We postulate that inaccurate measures of muscle mass may have obscured the role of obesity in sarcopenia and related outcomes. Our aim was to clarify the interactions of muscle and fat with physical performance and adverse outcomes using an accurate measure of muscle mass.