GENE-ENZYME RELATIONS OF TRYPTOPHAN MUTANTS IN STREPTOMYCES COELICOLOR A3(2) | Zendy

Charles M. Smithers | Zendy; Paulinus P. Engel | Zendy

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GENE-ENZYME RELATIONS OF TRYPTOPHAN MUTANTS IN STREPTOMYCES COELICOLOR A3(2)

Author(s) -

Charles M. Smithers,

Paulinus P. Engel

Publication year - 1974

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/78.3.799

Subject(s) - tryptophan synthase , streptomyces coelicolor , biology , mutant , tryptophan , genetics , enzyme , gene , microbiology and biotechnology , phosphoribosyltransferase , isomerase , biochemistry , hypoxanthine guanine phosphoribosyltransferase , amino acid

Mutations in twenty-eight tryptophan mutants of S. coelicolor A3(2) were mapped relative to the nearest flanking markers. Mutants lacking single enzymatic activities for phosphoribosyltransferase, phosphoribosylanthranilate isomerase, indodeglycerol phosphate synthase, tryptophan synthase A and tryptophan synthase B were identified.

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