Open AccessAn Analysis of Polygenes Affecting Wing Shape on Chromosome 2 in Drosophila melanogaster
Author(s) -
Kenneth Weber,
Robert C. Eisman,
Shawn Higgins,
Lisa Morey,
April Patty,
Michele Tausek,
ZhaoBang Zeng
Publication year - 2001
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/159.3.1045
Subject(s) - biology , drosophila melanogaster , genetics , wing , polygene , chromosome , drosophila (subgenus) , transposable element , drosophilidae , melanogaster , gene , dominance (genetics) , phenotype , quantitative trait locus , genome , engineering , aerospace engineering
Genetic effects on an index of wing shape on chromosome 2 of Drosophila melanogaster were mapped using isogenic recombinants with transposable element markers. At least 10 genes with small additive effects are dispersed evenly along the chromosome. Many interactions exist, with only small net effects in homozygous recombinants and little effect on phenotypic variance. Heterozygous chromosome segments show almost no dominance. Pleiotropic effects on leg shape are only minor. At first view, wing shape genes form a rather homogeneous class, but certain complexities remain unresolved.