A New Statistic for Detecting Genetic Differentiation | Zendy

Richard R. Hudson | Zendy

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A New Statistic for Detecting Genetic Differentiation

Author(s) -

Richard R. Hudson

Publication year - 2000

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/155.4.2011

Subject(s) - statistic , biology , range (aeronautics) , genetic data , statistics , genetics , mutation , summary statistics , evolutionary biology , mathematics , gene , demography , population , materials science , sociology , composite material

A new statistic for detecting genetic differentiation of subpopulations is described. The statistic can be calculated when genetic data are collected on individuals sampled from two or more localities. It is assumed that haplotypic data are obtained, either in the form of DNA sequences or data on many tightly linked markers. Using a symmetric island model, and assuming an infinite-sites model of mutation, it is found that the new statistic is as powerful or more powerful than previously proposed statistics for a wide range of parameter values.

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