Adaptive Mutation: Has the Unicorn Landed? | Zendy

Patricia L. Foster | Zendy

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Adaptive Mutation: Has the Unicorn Landed?

Author(s) -

Patricia L. Foster

Publication year - 1998

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/148.4.1453

Subject(s) - biology , adaptive mutation , mutation , genetics , reversion , allele , selection (genetic algorithm) , mechanism (biology) , adaptive evolution , point mutation , mutation rate , evolutionary biology , phenotype , gene , population , philosophy , demography , epistemology , artificial intelligence , sociology , computer science

Reversion of an episomal Lac− allele during lactose selection has been studied as a model for adaptive mutation. Although recent results show that the mutations that arise during selection are not “adaptive” in the original sense, the mutagenic mechanism that produces these mutations may nonetheless be of evolutionary significance. In addition, a transient mutational state induced in a subpopulation of starving cells could provide a species with a mechanism for adaptive evolution.

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