Mus spretus LINE-1s in the Mus musculus domesticus Inbred Strain C57BL/6J Are From Two Different Mus spretus LINE-1 Subfamilies | Zendy

Yingping Zhao | Zendy; Lorrie P. Daggett | Zendy; Stephen C. Hardies | Zendy

Open Access

Mus spretus LINE-1s in the Mus musculus domesticus Inbred Strain C57BL/6J Are From Two Different Mus spretus LINE-1 Subfamilies

Author(s) -

Yingping Zhao,

Lorrie P. Daggett,

Stephen C. Hardies

Publication year - 1996

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/142.2.549

Subject(s) - biology , subfamily , genetics , inbred strain , strain (injury) , lineage (genetic) , line (geometry) , gene , anatomy , geometry , mathematics

A LINE-1 element, LIC105, was found in the Mus musculus domesticus inbred strain, C57BL/6J. Upon sequencing, this element was found to belong to a M. spretus LINE-1 subfamily originating within the last 0.2 million years. This is the second spretus-specific LINE-1 subfamily found to be represented in C57BL/6J. Although it is unclear how these M. spretus LINE-1s transferred from M. spretus to M. m. domesticus, it is now clear that at least two different spretus LINE-1 sequences have recently transferred. The limited divergence between the C57BL/6J spretus-like LINE-1s and their closest spretus ancestors suggests that the transfer did not involve an exceptionally long lineage of sequential transpositions.

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