Open AccessCOMPLEMENTATION AND NONCOMPLEMENTATION AMONG NONALLELIC MUTATIONS ALTERING DEVELOPMENT IN SCHIZOPHYLLUM COMMUNE
Author(s) -
Keith K. Klein,
Carol S. Deppe
Publication year - 1985
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/109.2.333
Subject(s) - complementation , schizophyllum commune , genetics , biology , mutation , heterokaryon , gene , allele , mutant , biochemistry
Mutations resistant to compounds that alter the development of Schizophyllum commune (cyclic adenosine monophosphate, caffeine and imidazole) were selected. These mutations defined four genes, car (cAMP resistance), caf-1 and caf-2 (caffeine resistance) and imr (imidazole resistance). The mutations were found to be noncomplementing in certain pairs when tested against each other and against two previously isolated developmental mutations, B-con and sep (septateless), in fully compatible, forced heterokaryons. The pattern of complementation in fully compatible diploids showed noncomplementation only between allelic mutations, except for one case, imr vs. car.