Open AccessCOMPONENTS OF SELECTION IN X CHROMOSOME LINES OF DROSOPHILA MELANOGASTER: SEX RATIO MODIFICATION BY MEIOTIC DRIVE AND VIABILITY SELECTION
Author(s) -
James W. Curtsinger
Publication year - 1984
Publication title -
genetics (austin, tex.)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/108.4.941
Subject(s) - biology , meiotic drive , mendelian inheritance , genetics , selection (genetic algorithm) , meiosis , drosophila melanogaster , x chromosome , chromosome , sex ratio , line (geometry) , evolutionary biology , gene , population , demography , artificial intelligence , sociology , computer science , geometry , mathematics
Selection coefficients and segregation parameters have been estimated in 18 randomly chosen lines carrying wild X chromosomes on the cn bw genetic background. Each line was studied in replicated crosses of four types, with approximately 100 replications per line per cross. Crosses in which male X chromosomes differed exhibited significant sex ratio heterogeneity. Maximum likelihood estimation of segregation parameters revealed two lines in which the proportion of X-bearing gametes produced by males was significantly different from Mendelian expectations. These observations suggest that segregation distortion is a common feature of naturally occurring genetic variation. Non-Mendelian segregation has important evolutionary implications.