Open AccessFACTORS INFLUENCING DISPROPORTIONATE REPLICATION OF THE RIBOSOMAL RNA CISTRONS IN DROSOPHILA MELANOGASTER
Author(s) -
F. Lee Dutton,
Hallie M. Krider
Publication year - 1984
Publication title -
genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.792
H-Index - 246
eISSN - 1943-2631
pISSN - 0016-6731
DOI - 10.1093/genetics/107.3.395
Subject(s) - biology , genetics , drosophila melanogaster , dosage compensation , melanogaster , population , replication (statistics) , ribosomal rna , replication timing , x chromosome , gene , dna replication , demography , virology , sociology
This report describes studies of the compensatory response employing D. melanogaster stocks that bear cloned-X chromosomes derived from laboratory populations of strains Oregon R and Canton S. We find that modification of the autosomal background in either the female or the XY male parent influences the expression of the compensatory response by X chromosomes derived from the Canton S population, whereas Oregon R isolates are unresponsive to these effects. We have also studied compensatory replication in X/O larvae produced from cloned-X derivatives of both Canton S and Oregon R. Canton S larval compensation exceeds that of the adult, whereas in Oregon R the converse is true. We have concluded that both X chromosomal and autosomal factors affect the expression and magnitude of the compensatory response.