A CYTOGENETIC ANALYSIS OF THE CHROMOSOMAL REGION SURROUNDING THE α-GLYCEROPHOSPHATE DEHYDROGENASE LOCUS OF DROSOPHILA MELANOGASTER | Zendy

Michael A. Kotarski | Zendy; Sally Pickert | Zendy; Ross MacIntyre | Zendy

Open Access

A CYTOGENETIC ANALYSIS OF THE CHROMOSOMAL REGION SURROUNDING THE α-GLYCEROPHOSPHATE DEHYDROGENASE LOCUS OF DROSOPHILA MELANOGASTER

Author(s) -

Michael A. Kotarski,

Sally Pickert,

Ross MacIntyre

Publication year - 1983

Publication title -

genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.792

H-Index - 246

eISSN - 1943-2631

pISSN - 0016-6731

DOI - 10.1093/genetics/105.2.371

Subject(s) - polytene chromosome , biology , drosophila melanogaster , locus (genetics) , genetics , gene , chromosomal region , microbiology and biotechnology , chromosome , recombination , x chromosome , drosophilidae

The chromosomal region surrounding the structural gene for alpha-glycerophosphate dehydrogenase (alpha Gpdh, 2-20.5) of Drosophila melanogaster has been studied in detail. Forty-three EMS-induced recessive lethal mutations and five previously identified visible mutations have been localized within the 25A-27D region of chromosome 2 by deficiency mapping and in some cases by a recombination analysis. The 43 lethal mutations specify 17 lethal loci. alpha Gpdh has been localized to a single polytene chromosome band, 25F5, and there apparently are no lethals that map to the alpha Gpdh locus.

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