Tea polyphenol EGCG inhibited colorectal-cancer-cell proliferation and migration via downregulation of STAT3  | Zendy

Ke-Wang Luo | Zendy; Jun Xia | Zendy; BaoHui Cheng | Zendy; Hanchao Gao | Zendy; Liwu Fu | Zendy; Xinle Luo | Zendy

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Tea polyphenol EGCG inhibited colorectal-cancer-cell proliferation and migration via downregulation of STAT3

Author(s) -

Ke-Wang Luo,

Jun Xia,

BaoHui Cheng,

Hanchao Gao,

Liwu Fu,

Xinle Luo

Publication year - 2020

Publication title -

gastroenterology report

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.934

H-Index - 26

eISSN - 2052-0034

pISSN - 2304-1412

DOI - 10.1093/gastro/goaa072

Subject(s) - cell growth , cell migration , apoptosis , stat3 , annexin , western blot , microbiology and biotechnology , mtt assay , cancer research , cell , medicine , chemistry , biology , biochemistry , gene

Green tea is a popular beverage worldwide and epigallocatechin-3-gallate (EGCG) is the most bioactive polyphenol in green tea. Our study aims to investigate the anti-proliferation and anti-migration effects of EGCG against colorectal-cancer SW480, SW620, and LS411N cells, and elucidate the underlying mechanism.

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