
Transcriptional signatures of Mycobacterium tuberculosis in mouse model of intraocular tuberculosis
Author(s) -
Sudhanshu Abhishek,
Michelle B. Ryndak,
Alpa Choudhary,
Sumedha Sharma,
Amod Gupta,
Vishali Gupta,
Nirbhai Singh,
Suman Laal,
Indu Verma
Publication year - 2019
Publication title -
pathogens and disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.983
H-Index - 105
ISSN - 2049-632X
DOI - 10.1093/femspd/ftz045
Subject(s) - tuberculosis , mycobacterium tuberculosis , transcriptome , pathogenesis , biology , microarray , gene , downregulation and upregulation , polymerase chain reaction , microbiology and biotechnology , dna microarray , gene expression , medicine , immunology , pathology , genetics
Studies on human intraocular tuberculosis (IOTB) are extremely challenging. For understanding the pathogenesis of IOTB, it is important to investigate the mycobacterial transcriptional changes in ocular environment.