
Characterizing the arrhythmogenic substrate in personalized models of atrial fibrillation: sensitivity to mesh resolution and pacing protocol in AF models
Author(s) -
Patrick Boyle,
Alexander Ochs,
Rheeda L. Ali,
Nikhil Paliwal,
Natalia A. Trayanova
Publication year - 2021
Publication title -
europace
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.119
H-Index - 102
eISSN - 1532-2092
pISSN - 1099-5129
DOI - 10.1093/europace/euaa385
Subject(s) - medicine , atrial fibrillation , cardiology , protocol (science) , sensitivity (control systems) , pathology , electronic engineering , engineering , alternative medicine
Computationally guided persistent atrial fibrillation (PsAF) ablation has emerged as an alternative to conventional treatment planning. To make this approach scalable, computational cost and the time required to conduct simulations must be minimized while maintaining predictive accuracy. Here, we assess the sensitivity of the process to finite-element mesh resolution. We also compare methods for pacing site distribution used to evaluate inducibility arrhythmia sustained by re-entrant drivers (RDs).