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Long‐term association between self‐reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study
Author(s) -
Avery Christy L.,
Mills Katherine T.,
Chambless Lloyd E.,
Chang Patricia P.,
Folsom Aaron R.,
Mosley Thomas H.,
Ni Hanyu,
Rosamond Wayne D.,
Wagenknecht Lynne,
Wood Joy,
Heiss Gerardo
Publication year - 2010
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1093/eurjhf/hfp203
Subject(s) - medicine , atherosclerosis risk in communities , hazard ratio , heart failure , cohort , cohort study , population , diagnosis code , confidence interval , cardiology , physical therapy , environmental health
Aims Although studies of the accuracy of heart failure (HF) classification scoring systems are available, few have examined their performance when restricted to self‐reported items. Methods and results We evaluated the association between a simplified version of the Gothenburg score, a validated HF score comprised of cardiac and pulmonary signs and symptoms and medication use, and incident HF hospitalizations in 15 430 Atherosclerosis Risk in Communities (ARIC) Study participants. Gothenburg scores (range: 0–3) were constructed using self‐reported items obtained at study baseline (1987–89). Incident HF hospitalization over 14.7 years of follow‐up was defined as the first identified hospitalization with an ICD‐9 discharge code of 428 ( n = 1668). Self‐reported Gothenburg scores demonstrated very high agreement with the original metric comprised of self‐reported and clinical measures and were directly associated with incident HF hospitalizations: [score = 1: hazard rate ratio (HRR) = 1.23 (1.07–1.42); score = 2: HRR = 2.17 (1.92–2.43); score = 3: HRR = 3.98 (3.37–4.70)]. Conclusion In a population‐based cohort, self‐reported Gothenburg criteria items were associated with hospitalized HF over a prolonged follow‐up time. The association was also consistent across groups defined by sex and race, suggesting that this simple score deserves further study as a screening tool for the identification of individuals at high risk of HF in resource‐limited settings.