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Possible acute and chronic synergistic effect of dual chamber pacing and disopyramide in obstructive hypertrophic cardiomyopathy: a case report
Author(s) -
Haruki Shintaro,
Minami Yuichiro,
Kajimoto Katsuya,
Yashiro Bun,
Suzuki Tsuyoshi,
Kawana Masatoshi,
Hagiwara Nobuhisa
Publication year - 2010
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1093/eurjhf/hfp166
Subject(s) - disopyramide , medicine , ventricular outflow tract , cardiology , obstructive hypertrophic cardiomyopathy , hypertrophic cardiomyopathy , obstructive cardiomyopathy , cardiomyopathy , heart failure , catheter , surgery
It remains unclear whether the combination of dual‐chamber (DDD) pacing and disopyramide can achieve prolonged left ventricular outflow tract (LVOT) gradient reduction and symptom relief in patients with obstructive hypertrophic cardiomyopathy (HCM). In an HCM patient with a severe LVOT gradient, the combination of DDD pacing and disopyramide achieved marked improvement of gradient in the catheter laboratory and also after medium‐term follow‐up. The patient's severe dyspnoea was alleviated during the follow‐up period. This combination might enable physicians to treat and manage elderly symptomatic obstructive HCM patients with a severe LVOT gradient more effectively and less invasively.