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Continuous central haemodynamic measurements during the six‐minute walk test and daily life in patients with chronic heart failure
Author(s) -
Braunschweig Frieder,
Linde Cecilia,
Adamson Philip B.,
Magalski Anthony,
Erdmann Erland,
Kjellstrom Barbro,
Bennett Tom
Publication year - 2009
Publication title -
european journal of heart failure
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.149
H-Index - 133
eISSN - 1879-0844
pISSN - 1388-9842
DOI - 10.1093/eurjhf/hfp045
Subject(s) - medicine , hemodynamics , ambulatory , heart failure , cardiology , heart rate , diastole , pulmonary artery , blood pressure
Aims To compare haemodynamic responses during the 6‐min walk test (6MWT) and daily living activities in heart failure (HF) patients. Methods and results Eighteen HF patients received an implantable haemodynamic monitor, which continuously measured heart rate (HR), estimated pulmonary artery diastolic pressure (ePAD), and several right ventricular (RV) pressure parameters. During the 6MWT, haemodynamics were assessed at rest and peak exercise. Ambulatory values were measured as the daily minimum, maximum, and median, averaged over the 14‐day period surrounding each 6MWT. During the 6MWT, HR increased from 71 ± 17 to 101 ± 20 b.p.m. and ePAD from 20 ± 5 to 34 ± 8 mmHg. Daily minimum values were significantly lower and daily maximum values higher compared with rest and peak exercise. Patients with a walked distance above the median (402 m) had lower resting HR (64 ± 10 vs. 77 ± 20, P = 0.001) and ePAD (18 ± 4 vs. 21 ± 7, P = 0.022) compared to patients with walked distances below the median; values at peak exercise were similar. This pattern was also observed during the ambulatory periods. Conclusion Ranges of HR and RV pressures are significantly larger during daily living activities compared with 6MWT in HF patients. Haemodynamic characteristics of patients with greater exercise capacity include lower resting HR and RV pressures and are similar during the 6MWT and daily life.