Open AccessUnderstanding the genetics of adult-onset dilated cardiomyopathy: what a clinician needs to know
Author(s) -
Upasana Tayal,
James S. Ware,
Neal K. Lakdawala,
Stéphane Heymans,
Sanjay Prasad
Publication year - 2021
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehab286
Subject(s) - medicine , dilated cardiomyopathy , genetic testing , cardiomyopathy , relevance (law) , intensive care medicine , heart failure , political science , law
There is increasing understanding of the genetic basis to dilated cardiomyopathy and in this review, we offer a practical primer for the practising clinician. We aim to help all clinicians involved in the care of patients with dilated cardiomyopathy to understand the clinical relevance of the genetic basis of dilated cardiomyopathy, introduce key genetic concepts, explain which patients and families may benefit from genetic testing, which genetic tests are commonly performed, how to interpret genetic results, and the clinical applications of results. We conclude by reviewing areas for future research in this dynamic field.