Open AccessA cohort study and meta-analysis of isolated diastolic hypertension: searching for a threshold to guide treatment
Author(s) -
Alan P Jacobsen,
Mahmoud Al Rifai,
Kelly Arps,
Seamus P. Whelton,
Matthew J. Budoff,
Khurram Nasir,
Michael J. Blaha,
Bruce M. Psaty,
Roger S. Blumenthal,
Wendy S. Post,
John W. McEvoy
Publication year - 2021
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1093/eurheartj/ehab111
Subject(s) - medicine , hazard ratio , cardiology , blood pressure , odds ratio , cohort , diastole , proportional hazards model , cohort study , confidence interval
Whether isolated diastolic hypertension (IDH), as defined by the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline, is associated with cardiovascular disease (CVD) has been disputed. We aimed to further study the associations of IDH with (i) subclinical CVD in the form of coronary artery calcium (CAC), (ii) incident systolic hypertension, and (iii) CVD events.