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Termination of translation: interplay of mRNA, rRNAs and release factors?
Author(s) -
Kisselev Lev,
Ehrenberg Måns,
Frolova Ludmila
Publication year - 2003
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1093/emboj/cdg017
Subject(s) - biology , molecular cell biology , library science , microbiology and biotechnology , computer science
Termination of translation in eukaryotes has focused recently on functional anatomy of polypeptide chain release factor, eRF1, by using a variety of different approaches. The tight correlation between the domain structure and different functions of eRF1 has been revealed. Independently, the role of prokaryotic RF1/2 in GTPase activity of RF3 has been deciphered, as well as RF3 function itself.