Open AccessTransient ischaemic dilation and post-stress wall motion abnormality increase risk in patients with less than moderate ischaemia: analysis of the REFINE SPECT registry
Author(s) -
Robert J.H. Miller,
Lien-Hsin Hu,
Heidi Gransar,
Julián Betancur,
Evann Eisenberg,
Yuka Otaki,
Tali Sharir,
Mathews B. Fish,
Terrence D. Ruddy,
Sharmila Dorbala,
Marcelo Di Carli,
Andrew J. Einstein,
Philipp A. Kaufmann,
Albert J. Sinusas,
Edward J. Miller,
Timothy M. Bateman,
Guido Germano,
Balaji Tamarappoo,
Damini Dey,
Daniel S. Berman,
Piotr J. Slomka
Publication year - 2019
Publication title -
european heart journal. cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.576
H-Index - 92
eISSN - 2047-2412
pISSN - 2047-2404
DOI - 10.1093/ehjci/jez172
Subject(s) - medicine , mace , hazard ratio , cardiology , ischemia , perfusion , myocardial perfusion imaging , proportional hazards model , single photon emission computed tomography , nuclear medicine , myocardial infarction , confidence interval , conventional pci
Ischaemia on single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is strongly associated with cardiovascular risk. Transient ischaemic dilation (TID) and post-stress wall motion abnormalities (WMA) are non-perfusion markers of ischaemia with incremental prognostic utility. Using a large, multicentre SPECT MPI registry, we assessed the degree to which these features increased the risk of major adverse cardiovascular events (MACE) in patients with less than moderate ischaemia.