
End of Induction Patient-reported Outcomes Predict Clinical Remission but Not Endoscopic Remission in Crohn’s Disease
Author(s) -
Emily C L Wong,
Elisa Buffone,
So Jeong Lee,
Parambir S. Dulai,
John K. Marshall,
Walter Reinisch,
Neeraj Narula
Publication year - 2020
Publication title -
journal of crohn's and colitis
Language(s) - English
Resource type - Journals
eISSN - 1876-4479
pISSN - 1873-9946
DOI - 10.1093/ecco-jcc/jjaa242
Subject(s) - medicine , odds ratio , confidence interval , crohn's disease , confounding , gastroenterology , logistic regression , post hoc analysis , infliximab , severity of illness , disease
It is unclear whether early symptom improvement in Crohn's disease [CD] provides any prognostic information for patients long-term. This paper aims to investigate the relationship between early patient-reported outcomes [PROs] after completion of induction of infliximab, and their relationship with long-term clinical remission [CR] and endoscopic remission [ER].