HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure
Author(s) -
Beth A. Firulli,
Rajani M. George,
Jade Harkin,
Kevin P. Toolan,
Hongyu Gao,
Yunlong Liu,
Wenjun Zhang,
Loren J. Field,
Ying Liu,
Weinian Shou,
R. Mark Payne,
Michael Rubartvon der Lohe,
Anthony B. Firulli
Publication year - 2019
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvz182
Subject(s) - embryonic heart , ventricle , heart development , heart failure , embryonic stem cell , medicine , biology , cardiology , microbiology and biotechnology , anatomy , gene , genetics
To examine the role of the basic Helix-loop-Helix (bHLH) transcription factor HAND1 in embryonic and adult myocardium.
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