Open AccessHAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure
Author(s) -
Beth A. Firulli,
Rajani M. George,
Jade Harkin,
Kevin P. Toolan,
Hongyu Gao,
Yunlong Liu,
Wenjun Zhang,
Loren J. Field,
Ying Li,
Weinian Shou,
R. Mark Payne,
Michael Rubart-von der Lohe,
Beth A. Firulli
Publication year - 2019
Publication title -
cardiovascular research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.774
H-Index - 219
eISSN - 1755-3245
pISSN - 0008-6363
DOI - 10.1093/cvr/cvz182
Subject(s) - embryonic heart , ventricle , heart development , embryonic stem cell , heart failure , microbiology and biotechnology , myocyte , medicine , biology , cardiology , anatomy , gene , genetics
To examine the role of the basic Helix-loop-Helix (bHLH) transcription factor HAND1 in embryonic and adult myocardium.