Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: a randomized trial of atorvastatin | Zendy

Raja Jayaram | Zendy; Michael Jones | Zendy; Svetlana Reilly | Zendy; Mark J. Crabtree | Zendy; Nikhil Pal | Zendy; Nicola Goodfellow | Zendy; Keshav Nahar | Zendy; Jillian N. Simon | Zendy; Ricardo Carnicer | Zendy; Ravi DeSilva | Zendy; Chandana Ratnatunga | Zendy; Mario Petrou | Zendy; Rana Sayeed | Zendy; Andrea Roalfe | Zendy; Keith M. Chan | Zendy; Yaver Bashir | Zendy; Timothy R. Betts | Zendy; Michael Hill | Zendy; Barbara Casadei | Zendy

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Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: a randomized trial of atorvastatin

Author(s) -

Raja Jayaram,

Michael Jones,

Svetlana Reilly,

Mark J. Crabtree,

Nikhil Pal,

Nicola Goodfellow,

Keshav Nahar,

Jillian N. Simon,

Ricardo Carnicer,

Ravi DeSilva,

Chandana Ratnatunga,

Mario Petrou,

Rana Sayeed,

Andrea Roalfe,

Keith M. Chan,

Yaver Bashir,

Timothy R. Betts,

Michael Hill,

Barbara Casadei

Publication year - 2020

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvaa302

Subject(s) - atorvastatin , medicine , randomized controlled trial , refractory period , cardiology , balance (ability) , cardiac surgery , physical therapy

Systemic inflammation and increased activity of atrial NOX2-containing NADPH oxidases have been associated with the new onset of atrial fibrillation (AF) after cardiac surgery. In addition to lowering LDL-cholesterol, statins exert rapid anti-inflammatory and antioxidant effects, the clinical significance of which remains controversial.

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