Dietary carbohydrates restriction inhibits the development of cardiac hypertrophy and heart failure | Zendy

Michinari Nakamura | Zendy; Natalija Odanović | Zendy; Yasuki Nakada | Zendy; Satomi Dohi | Zendy; Peiyong Zhai | Zendy; Andreas S. Ivessa | Zendy; Zhi Yang | Zendy; Maha Abdellatif | Zendy; Junichi Sadoshima | Zendy

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Dietary carbohydrates restriction inhibits the development of cardiac hypertrophy and heart failure

Author(s) -

Michinari Nakamura,

Natalija Odanović,

Yasuki Nakada,

Satomi Dohi,

Peiyong Zhai,

Andreas S. Ivessa,

Zhi Yang,

Maha Abdellatif,

Junichi Sadoshima

Publication year - 2020

Publication title -

cardiovascular research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.774

H-Index - 219

eISSN - 1755-3245

pISSN - 0008-6363

DOI - 10.1093/cvr/cvaa298

Subject(s) - heart failure , cardiology , cardiac hypertrophy , medicine , muscle hypertrophy , endocrinology

A diet with modified components, such as a ketogenic low-carbohydrate (LC) diet, potentially extends longevity and healthspan. However, how an LC diet impacts on cardiac pathology during haemodynamic stress remains elusive. This study evaluated the effects of an LC diet high in either fat (Fat-LC) or protein (Pro-LC) in a mouse model of chronic hypertensive cardiac remodelling.

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