Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections
Author(s) -
Laura Fanucchi,
Sharon Walsh,
Alice Thornton,
Paul A. Nuzzo,
Michelle R. Lofwall
Publication year - 2019
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciz654
Subject(s) - medicine , buprenorphine , antimicrobial , opioid use disorder , clinical trial , randomized controlled trial , opioid , antibiotics , intensive care medicine , emergency medicine , surgery , chemistry , receptor , organic chemistry , microbiology and biotechnology , biology
In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days.
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