Open AccessA Balanced Proinflammatory and Regulatory Cytokine Signature in Young African Children Is Associated With Lower Risk of Clinical Malaria
Author(s) -
Carlota Dobaño,
Augusto Nhabomba,
Maria Nélia Manaca,
Tamara Berthoud,
Ruth Aguilar,
Llorenç Quintó,
Arnoldo Barbosa,
Margarita Rodríguez,
Alfons Jiménez,
Penny Groves,
Rebeca Santano,
Quique Bassat,
John J. Aponte,
Caterina Guinovart,
Denise L. Doolan,
Pedro L. Alonso
Publication year - 2018
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciy934
Subject(s) - immunology , medicine , malaria , cytokine , proinflammatory cytokine , chemoprophylaxis , artesunate , plasmodium falciparum , inflammation
The effect of timing of exposure to first Plasmodium falciparum infections during early childhood on the induction of innate and adaptive cytokine responses and their contribution to the development of clinical malaria immunity is not well established.