Ultrasensitive and Quantitative Toxin Measurement Correlates With Baseline Severity, Severe Outcomes, and Recurrence Among Hospitalized Patients With Clostridioides difficile Infection | Zendy

Carolyn D. Alonso | Zendy; Ciarán P. Kelly | Zendy; Kevin W. Garey | Zendy; Anne J Gonzales-Luna | Zendy; David N. Williams | Zendy; Kaitlyn Daugherty | Zendy; Christine Cuddemi | Zendy; Javier Villafuerte-Gálvez | Zendy; Nicole White | Zendy; Xinhua Chen | Zendy; Hua Xu | Zendy; Rebecca Sprague | Zendy; Caitlin Barrett | Zendy; Mark A. Miller | Zendy; Agnès Foussadier | Zendy; Aude Lantz | Zendy; Alice Banz | Zendy; Nira R. Pollock | Zendy

Open Access

Ultrasensitive and Quantitative Toxin Measurement Correlates With Baseline Severity, Severe Outcomes, and Recurrence Among Hospitalized Patients With Clostridioides difficile Infection

Author(s) -

Carolyn D. Alonso,

Ciarán P. Kelly,

Kevin W. Garey,

Anne J Gonzales-Luna,

David N. Williams,

Kaitlyn Daugherty,

Christine Cuddemi,

Javier Villafuerte-Gálvez,

Nicole White,

Xinhua Chen,

Hua Xu,

Rebecca Sprague,

Caitlin Barrett,

Mark A. Miller,

Agnès Foussadier,

Aude Lantz,

Alice Banz,

Nira R. Pollock

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab826

Subject(s) - medicine , interquartile range , clostridioides , gastroenterology , toxin , feces , diarrhea , clostridium difficile toxin a , clostridium difficile , antibiotics , microbiology and biotechnology , biology

Stool toxin concentrations may impact Clostridioides difficile infection (CDI) severity and outcomes. We correlated fecal C difficile toxin concentrations, measured by an ultrasensitive and quantitative assay, with CDI baseline severity, attributable outcomes, and recurrence.

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