Microbial Cell-Free DNA Identifies Etiology of Bloodstream Infections, Persists Longer Than Conventional Blood Cultures, and Its Duration of Detection Is Associated With Metastatic Infection in Patients With Staphylococcus aureus and Gram-Negative Bacteremia | Zendy

Emily M. Eichenberger | Zendy; Christiaan R. de Vries | Zendy; Felicia Ruffin | Zendy; Batu K. SharmaKuinkel | Zendy; Lawrence Park | Zendy; David K. Hong | Zendy; Erick R. Scott | Zendy; Lily Blair | Zendy; Nicholas Degner | Zendy; Desiree Hollemon | Zendy; Timothy A. Blauwkamp | Zendy; Carine Ho | Zendy; Hon Seng | Zendy; Pratik Shah | Zendy; Lisa Wanda | Zendy; Vance G. Fowler | Zendy; Asim A. Ahmed | Zendy

Open Access

Microbial Cell-Free DNA Identifies Etiology of Bloodstream Infections, Persists Longer Than Conventional Blood Cultures, and Its Duration of Detection Is Associated With Metastatic Infection in Patients With Staphylococcus aureus and Gram-Negative Bacteremia

Author(s) -

Emily M. Eichenberger,

Christiaan R. de Vries,

Felicia Ruffin,

Batu K. SharmaKuinkel,

Lawrence Park,

David K. Hong,

Erick R. Scott,

Lily Blair,

Nicholas Degner,

Desiree Hollemon,

Timothy A. Blauwkamp,

Carine Ho,

Hon Seng,

Pratik Shah,

Lisa Wanda,

Vance G. Fowler,

Asim A. Ahmed

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab742

Subject(s) - bacteremia , odds ratio , medicine , blood culture , pathogen , staphylococcus aureus , etiology , staphylococcal infections , confidence interval , bloodstream infection , immunology , gastroenterology , microbiology and biotechnology , biology , antibiotics , bacteria , genetics

Microbial cell-free DNA (mcfDNA) sequencing of plasma can identify the presence of a pathogen in a host. In this study, we evaluated the duration of pathogen detection by mcfDNA sequencing vs conventional blood culture in patients with bacteremia.

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