Evaluating the Presence of Replication-Competent Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From Nursing Home Residents With Persistently Positive Reverse Transcription Polymerase Chain Reaction (RT-PCR) Results
Author(s) -
Joseph D. Lutgring,
Farrell A. Tobolowsky,
Kelly M Hatfield,
Nicholas Lehnertz,
Maureen Sullivan,
Karen G Martin,
Amelia A. Keaton,
D Joseph Sexton,
Azaibi Tamin,
Jennifer L. Harcourt,
Natalie J. Thornburg,
Sujan Reddy,
John A. Jernigan
Publication year - 2021
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab436
Subject(s) - medicine , coronavirus , polymerase chain reaction , covid-19 , reverse transcription polymerase chain reaction , virology , replication (statistics) , virus , respiratory system , nursing homes , betacoronavirus , viral replication , disease , infectious disease (medical specialty) , gene , nursing , biology , messenger rna , genetics , outbreak
Replication-competent virus has not been detected in individuals with mild to moderate coronavirus disease 2019 (COVID-19) more than 10 days after symptom onset. It is unknown whether these findings apply to nursing home residents. Of 273 specimens collected from nursing home residents >10 days from the initial positive test, none were culture positive.
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