Open AccessColonization With Fluoroquinolone-Resistant Enterobacterales Decreases the Effectiveness of Fluoroquinolone Prophylaxis in Hematopoietic Cell Transplant Recipients
Author(s) -
Michael J. Satlin,
Liang Chen,
Claire Douglass,
Michael Hovan,
Emily Davidson,
Rosemary Soave,
Marisa La Spina,
Alexandra Gomez-Arteaga,
Koen van Besien,
Sebastian Mayer,
Adrienne A. Phillips,
Jingmei Hsu,
Rianna Malherbe,
Catherine B. Small,
Stephen G. Jenkins,
Lars F. Westblade,
Barry N Kreiswirth,
Thomas J. Walsh
Publication year - 2021
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab404
Subject(s) - levofloxacin , medicine , neutropenia , antibiotics , colonization , broth microdilution , transplantation , antibacterial agent , febrile neutropenia , microbiology and biotechnology , chemotherapy , minimum inhibitory concentration , biology
Levofloxacin prophylaxis is recommended to prevent gram-negative bloodstream infections (BSIs) in patients with prolonged chemotherapy-induced neutropenia. However, increasing fluoroquinolone resistance may decrease the effectiveness of this approach.