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Severe Acute Respiratory Syndrome Coronavirus 2 Infection Among Healthcare Workers in South Africa: A Longitudinal Cohort Study
Author(s) -
Marta C. Nunes,
Vicky L. Baillie,
Gaurav Kwatra,
Sutika Bhikha,
Charl Verwey,
Colin Menezes,
Clare Cutland,
David P. Moore,
Ziyaad Dangor,
Yasmin Adam,
R L Mathivha,
Sithembiso Velaphi,
Merika Tsitsi,
Ricardo Águas,
Shabir A. Madhi,
Firdose Nakwa,
Sarah van Blydenstein,
Michelle Venter,
Denasha L. Reddy,
Jeanine du Plessis,
Matt Laubscher,
Lara Van Der Merwe,
Nkululeko Mbele,
Beya Mukendi,
Shakeel McKenzie,
Sihle Mtshali,
Christian K. Mukendi,
Ayanda Nzimande,
Wendy Zimkhitha Mandindi,
Amit J Nana,
Martin Mosotho Rafuma,
Masego Nicole Mathibe,
Andrew Moultrie
Publication year - 2021
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab398
Subject(s) - medicine , asymptomatic , cohort , serology , confidence interval , cohort study , coronavirus , health care , immunology , covid-19 , infectious disease (medical specialty) , disease , antibody , economics , economic growth
From April to September 2020, we investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in a cohort of 396 healthcare workers (HCWs) from 5 departments at Chris Hani Baragwanath Hospital, South Africa. Overall, 34.6% of HCWs had polymerase chain reaction-confirmed SARS-CoV-2 infection (132.1 [95% confidence interval, 111.8-156.2] infections per 1000 person-months); an additional 27 infections were identified by serology. HCWs in the internal medicine department had the highest rate of infection (61.7%). Among polymerase chain reaction-confirmed cases, 10.4% remained asymptomatic, 30.4% were presymptomatic, and 59.3% were symptomatic.

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