Single Dose of an mRNA Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) Vaccine Is Associated With Lower Nasopharyngeal Viral Load Among Nursing Home Residents With Asymptomatic Coronavirus Disease 2019 (COVID-19) | Zendy

M. Catherine McEllistrem | Zendy; Cornelius J. Clancy | Zendy; Deanna J. Buehrle | Zendy; Aaron Lucas | Zendy; Brooke K. Decker | Zendy

Open Access

Single Dose of an mRNA Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) Vaccine Is Associated With Lower Nasopharyngeal Viral Load Among Nursing Home Residents With Asymptomatic Coronavirus Disease 2019 (COVID-19)

Author(s) -

M. Catherine McEllistrem,

Cornelius J. Clancy,

Deanna J. Buehrle,

Aaron Lucas,

Brooke K. Decker

Publication year - 2021

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciab263

Subject(s) - medicine , asymptomatic , vaccination , viral load , outbreak , coronavirus , covid-19 , virology , transmission (telecommunications) , asymptomatic carrier , immunology , disease , virus , infectious disease (medical specialty) , electrical engineering , engineering

In nursing home residents with asymptomatic COVID-19 diagnosed through twice-weekly surveillance testing, single-dose BNT162b2 vaccination (Pfizer-BioNTech) was associated with -2.4 mean log10 lower nasopharyngeal viral load than detected in absence of vaccination (P = .004). Since viral load is linked to transmission, single-dose mRNA SARS-CoV-2 vaccination may help control outbreaks.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research