Open AccessBaseline Neurocognitive Impairment (NCI) Is Associated With Incident Frailty but Baseline Frailty Does Not Predict Incident NCI in Older Persons With Human Immunodeficiency Virus (HIV)
Author(s) -
Mary Clare Masters,
Jeremiah Perez,
Kun Wu,
Ronald J. Ellis,
Karl Goodkin,
Susan L. Koletar,
Adriana Andrade,
Jingyan Yang,
Todd T. Brown,
Frank J. Palella,
Ned Sacktor,
Katherine Tassiopoulos,
Kristine M. Erlandson
Publication year - 2021
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab122
Subject(s) - medicine , neurocognitive , confounding , interquartile range , multicenter aids cohort study , confidence interval , odds ratio , gerontology , cohort , cohort study , human immunodeficiency virus (hiv) , cognition , immunology , viral load , psychiatry , antiretroviral therapy
Neurocognitive impairment (NCI) and frailty are more prevalent among persons with human immunodeficiency virus (HIV, PWH) compared to those without HIV. Frailty and NCI often overlap with one another. Whether frailty precedes declines in neurocognitive function among PWH or vice versa has not been well established.