Open AccessA Genome-Wide Association Study Identifies Novel Susceptibility loci in Chronic Chagas Cardiomyopathy
Author(s) -
Desiré Casares-Marfil,
Mariana Strauss,
Pau Bosch-Nicolau,
María Silvina Lo Presti,
Israel Molina,
Christophe Chevillard,
Edécio CunhaNeto,
Éster Cerdeira Sabino,
Antônio Luiz Pinho Ribeiro,
Clara Isabel González,
Javier Martı́n,
Marialbert AcostaHerrera
Publication year - 2021
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciab090
Subject(s) - chagas disease , genome wide association study , cardiomyopathy , genetic association , trypanosoma cruzi , in silico , genetics , disease , medicine , biology , triatominae , gene , single nucleotide polymorphism , immunology , genotype , parasite hosting , heart failure , world wide web , computer science
Chagas disease is an infectious disease caused by the parasite Trypanosoma cruzi and is endemic from Latin American countries. The goal of our study was to identify novel genetic loci associated with chronic Chagas cardiomyopathy development in Chagas disease patients from different Latin American populations.