The Immunoglobulin M-Shed Acute Phase Antigen (SAPA)-test for the Early Diagnosis of Congenital Chagas Disease in the Time of the Elimination Goal of Mother-to-Child Transmission | Zendy

Yagahira E. Castro-Sesquen | Zendy; Freddy Tinajeros | Zendy; Caryn Bern | Zendy; Gerson GaldosCardenas | Zendy; Edith Málaga | Zendy; Edward Valencia Ayala | Zendy; Kathryn A. Hjerrild | Zendy; Steven J. Clipman | Zendy; Andrés G. Lescano | Zendy; Tabitha Bayangos | Zendy; Walter Castillo-Urquiaga | Zendy; María Carmen Menduiña | Zendy; Kawsar R. Talaat | Zendy; Robert H. Gilman | Zendy

Open Access

The Immunoglobulin M-Shed Acute Phase Antigen (SAPA)-test for the Early Diagnosis of Congenital Chagas Disease in the Time of the Elimination Goal of Mother-to-Child Transmission

Author(s) -

Yagahira E. Castro-Sesquen,

Freddy Tinajeros,

Caryn Bern,

Gerson GaldosCardenas,

Edith Málaga,

Edward Valencia Ayala,

Kathryn A. Hjerrild,

Steven J. Clipman,

Andrés G. Lescano,

Tabitha Bayangos,

Walter Castillo-Urquiaga,

María Carmen Menduiña,

Kawsar R. Talaat,

Robert H. Gilman

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa986

Subject(s) - chagas disease , cohort , medicine , immunology , antibody , pediatrics , cohort study , antigen

Diagnosis of congenital Chagas disease (CChD) in most endemic areas is based on low-sensitive microscopy at birth and 9-month immunoglobulin G (IgG), which has poor adherence. We aim to evaluate the accuracy of the Immunoglobulin M (IgM)-Shed Acute Phase Antigen (SAPA) test in the diagnosis of CChD at birth.

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