Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100–200 Cells/µL in Botswana | Zendy

Mark W. Tenforde | Zendy; Thandi Milton | Zendy; Ikanyeng Rulaganyang | Zendy; Charles Muthoga | Zendy; Leabaneng Tawe | Zendy; Tom Chiller | Zendy; Greg Greene | Zendy; Alexander Jordan | Zendy; Christopher G. Williams | Zendy; Leah A. Owen | Zendy; Tshepo Leeme | Zendy; Amber Boose | Zendy; Julia Ngidi | Zendy; Madisa Mine | Zendy; Joseph N Jarvis | Zendy

Open Access

Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100–200 Cells/µL in Botswana

Author(s) -

Mark W. Tenforde,

Thandi Milton,

Ikanyeng Rulaganyang,

Charles Muthoga,

Leabaneng Tawe,

Tom Chiller,

Greg Greene,

Alexander Jordan,

Christopher G. Williams,

Leah A. Owen,

Tshepo Leeme,

Amber Boose,

Julia Ngidi,

Madisa Mine,

Joseph N Jarvis

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa899

Subject(s) - human immunodeficiency virus (hiv) , antigen , medicine , immunology , virology , virus

Increasing the CD4-count threshold for cryptococcal antigen (CrAg) screening from ≤100 to ≤200 cells/µL resulted in a 3-fold increase in numbers screened. CrAg-prevalence was 3.5% at CD4 101-200 and 6.2% ≤100 cells/µL. Six-month mortality was 21.4% (9/42) in CrAg-positive CD4 ≤100 cells/µL and 3.2% (1/31) in CrAg-positive CD4 101-200 cells/µL.

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