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C-Reactive Protein, Procalcitonin, and White Blood Count to Rule Out Neonatal Early-onset Sepsis Within 36 Hours: A Secondary Analysis of the Neonatal Procalcitonin Intervention Study
Author(s) -
Martin Stocker,
Wendy van Herk,
Salhab el Helou,
Sourabh Dutta,
Frank A B A Schuerman,
Rita K. van den Tooren-de Groot,
Jantien W. Wieringa,
Jan Janota,
Laura H van der Meer-Kappelle,
Rob Moonen,
Sintha D. Sie,
Esther de Vries,
Albertine E. Donker,
Urs Zimmerman,
Luregn J. Schlapbach,
Amerik C. de Mol,
Angelique Hoffman-Haringsma,
Madan Roy,
Maren Tomaske,
René F. Kornelisse,
Juliette van Gijsel,
Eline G. Visser,
Frans B. Plötz,
Paul T. Heath,
Niek B. Achten,
Dirk Lehnick,
Annemarie M. C. van Rossum
Publication year - 2020
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciaa876
Subject(s) - procalcitonin , medicine , sepsis , neonatal sepsis , c reactive protein , white blood cell , antibiotics , antibiotic therapy , blood culture , gastroenterology , biomarker , area under the curve , inflammation , biochemistry , chemistry , microbiology and biotechnology , biology
Neonatal early-onset sepsis (EOS) is one of the main causes of global neonatal mortality and morbidity, and initiation of early antibiotic treatment is key. However, antibiotics may be harmful.

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