Alterations of the Oral Microbiome and Cumulative Carbapenem Exposure Are Associated With Stenotrophomonas maltophilia Infection in Patients With Acute Myeloid Leukemia Receiving Chemotherapy | Zendy

Samuel L Aitken | Zendy; Pranoti Sahasrabhojane | Zendy; Dimitrios P. Kontoyiannis | Zendy; Tor Savidge | Zendy; César A. Arias | Zendy; Nadim J. Ajami | Zendy; Samuel A. Shelburne | Zendy; Jessica Galloway-Peña | Zendy

Open Access

Alterations of the Oral Microbiome and Cumulative Carbapenem Exposure Are Associated With Stenotrophomonas maltophilia Infection in Patients With Acute Myeloid Leukemia Receiving Chemotherapy

Author(s) -

Samuel L Aitken,

Pranoti Sahasrabhojane,

Dimitrios P. Kontoyiannis,

Tor Savidge,

César A. Arias,

Nadim J. Ajami,

Samuel A. Shelburne,

Jessica Galloway-Peña

Publication year - 2020

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciaa778

Subject(s) - stenotrophomonas maltophilia , medicine , myeloid leukemia , hazard ratio , pneumonia , meropenem , leukemia , gastroenterology , immunology , microbiology and biotechnology , antibiotics , confidence interval , pseudomonas aeruginosa , antibiotic resistance , biology , bacteria , genetics

Stenotrophomonas maltophilia is increasingly common in patients with acute myeloid leukemia (AML). Little is known about factors that drive S. maltophilia infection. We evaluated the microbiome and cumulative antibiotic use as predictors of S. maltophilia infection in AML patients receiving remission induction chemotherapy (RIC).

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