Open AccessConcordance of Drug-resistance Profiles Between Persons With Drug-resistant Tuberculosis and Their Household Contacts: A Systematic Review and Meta-analysis
Author(s) -
Silvia S. Chiang,
Meredith B. Brooks,
Harri Jenkins,
Dana Rubenstein,
James A Seddon,
Brittney van de Water,
Michael M. Lindeborg,
Mercedes C. Becerra,
Courtney M. Yuen
Publication year - 2020
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciaa613
Subject(s) - concordance , medicine , isoniazid , tuberculosis , meta analysis , drug resistance , confidence interval , mycobacterium tuberculosis , regimen , disease , pathology , biology , microbiology and biotechnology
Household contacts of patients with drug-resistant tuberculosis (TB) are at high risk for being infected with Mycobacterium tuberculosis and for developing TB disease. To guide regimen composition for the empirical treatment of TB infection and disease in these household contacts, we estimated drug-resistance profile concordance between index patients with drug-resistant TB and their household contacts.