High Incidence of Herpes Zoster After Cord Blood Hematopoietic Cell Transplant Despite Longer Duration of Antiviral Prophylaxis
Author(s) -
Elisabetta Xue,
Hu Xie,
Wendy M. Leisenring,
Louise E. Kimball,
Sonia Goyal,
E Chung,
Rachel Blazevic,
Byron Maltez,
A. S. Edwards,
Ann Dahlberg,
Rachel B. Salit,
Colleen Delaney,
Steven A. Pergam,
Michael Boeckh,
Filippo Milano,
Joshua A. Hill
Publication year - 2020
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciaa222
Subject(s) - medicine , cumulative incidence , hazard ratio , incidence (geometry) , confidence interval , proportional hazards model , context (archaeology) , cohort , hematopoietic cell , surgery , haematopoiesis , paleontology , physics , genetics , stem cell , optics , biology
Cord blood transplant (CBT) recipients have a high incidence of herpes zoster (HZ) in the context of short-term peritransplant antiviral prophylaxis. In 2009, international guidelines recommended HZ prophylaxis for at least 1 year after hematopoietic cell transplant. The impact of longer-term antiviral prophylaxis on HZ incidence after CBT is unknown.
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